今回は2型糖尿病と歯周病の関連を検討した文献です。

歯周病ブログ①と似た目的で、今回は台湾の大学病院で

健診受診者を対象に調査されたものです。

CPIを評価項目、2型糖尿病を暴露要因として

2型糖尿病患者と非糖尿病者の歯周病有病率を調査しています。

We investigated the association between type 2 diabetes mellitus (T2DM) and periodontal disease (PD) in the context of the current periodontal aetiology model.

In total, 14,747 community residents aged 35-44 years were invited to a community-based PD survey between 2003 and 2006 using the community periodontal index. Significant factors modifying the association between T2DM and PD were ascertained. We further assessed the association between T2DM and the risk for PD, within strata of significant effect modifiers, after controlling for other putative factors.

The prevalence rate was 10% higher in subjects with T2DM than in those without. After controlling for significant factors, T2DM was positively associated with the risk for PD (adjusted odds ratio=1.34,95% confidence interval: 1.07-1.74). The results of interaction assessment showed that only the waist was identified as a statistically significant effect modifier for such a positive association.

The association between T2DM and the risk for PD among young adult was demonstrated. This finding, together with other aetiological factors, fit with the current hypothesized model of the aetiology of periodontitis. However, the effect of T2DM modified by waist measurement should be verified in future studies.

つまり

35～44歳の2型糖尿病患者では歯周病有病率が10％以上高く

歯周病リスクに対する 調整オッズ比は1.34だったとうことです。

今回も結論として

2型糖尿病は歯周病有病率を上昇させるというものでした。

引用文献

Wang TT¹, Chen TH, Wang PE, Lai H, Lo MT, Chen PY, Chiu SY.

A population-based study on the association between type 2 diabetes and periodontal disease in 12,123 middle-aged Taiwanese (KCIS No. 21).

J Clin Periodontol. 2009 May;36(5):372-9.