今回も糖尿病と歯周病の関連についての文献です。
1型・2型患者と非糖尿病者の歯周病の有病率と歯周病の
広がり(アタッチメントロスと喪失歯数)を
比較しています。
AIM:
The aim of this study was to determine whether both type 1 (T1DM) and type 2 diabetes mellitus (T2DM) are associated with increased prevalence and extent of periodontal disease and tooth loss compared with non-diabetic subjects within a homogeneous adult study population.
MATERIAL AND METHODS:
T1DM, T2DM and non-diabetic subjects were recruited from the population-based Study of Health in Pomerania. Additionally, T1DM subjects were retrieved from a Diabetes Centre. The total study population comprised 145 T1DM and 2647 non-diabetic subjects aged 20-59 years, and 182 T2DM and 1314 non-diabetic subjects aged 50-81 years. Periodontal disease was assessed by attachment loss (AL) and the number of missing teeth.
RESULTS:
Multivariable regression revealed an association between T1DM (p<0.001) and T2DM (p<0.01) with mean AL after full adjustment. After age stratification (p=0.04 for interaction), the effect of T2DM was only statistically significant in the 60-69-year-old subjects (B=0.90 (95% confidence intervals [95% CI]; 0.49, 1.31). T1DM was positively associated with tooth loss (adjusted, p<0.001). The association between T2DM and tooth loss was statistically significant only for females (odds ratios=1.60 [95% CI: 1.10, 2.33]).
CONCLUSIONS:
Our study confirmed an association between both T1DM and T2DM with periodontitis and tooth loss. Therefore, oral health education should be promoted in diabetic subjects.
つまり
年代別では、60代のみ2型患者は
非糖尿病者よりアタッチメントレベルが有意に増加し
1型患者では40代と50代において喪失歯数が有意に増加し
女性に限ると2型患者では喪失歯数が有意に増加しており
結論として、やはり1型2型共に糖尿病は
歯周病の重症度と歯の喪失を増加させるということです。
引用文献
Kaur G1, Holtfreter B, Rathmann W, Schwahn C, Wallaschofski H, Schipf S, Nauck M, Kocher T.
Association between type 1 and type 2 diabetes with periodontal disease and tooth loss.
J Clin Periodontol. 2009 Sep;36(9):765-74.