今回も妊婦の患者に歯周治療を行うことで

早産抑制効果があるか調べた文献です。

アメリカの産婦人科クリニックでの調査です。

757名の歯周病に罹患している妊娠6～20週

の妊婦の内、378名に介入し

残りは非介入です。

介入グループにはDHによる

SRPを含む専門的口腔ケアを行っています。

The purpose of this study was to test whether treating periodontal disease (PD) in pregnancy will reduce the incidence of spontaneous preterm delivery (SPTD) at < or = 35 weeks of gestation.

A multicenter, randomized clinical trial was performed. Subjects with PD were randomized to scaling and root planing (active) or tooth polishing (control). The primary outcome was the occurrence of SPTD at <35 weeks of gestation.

We screened 3563 subjects for PD; the prevalence of PD was 50%. Seven hundred fifty-seven subjects were assigned randomly; 378 subjects were assigned to the active group, and 379 subjects were assigned to the placebo group. Active treatment did not reduce the risk of SPTD at <35 weeks of gestation (relative risk, 1.19; 95% confidence interval [CI], 0.62-2.28) or composite neonatal morbidity (relative risk, 1.30; 95% CI, 0.83-2.04). There was a suggestion of an increase in the risk of indicated SPTD at <35 weeks of gestation in those subjects who received active treatment (relative risk, 3.01; 95% CI, 0.95-4.24).

Treating periodontal disease does not reduce the incidence of SPTD.

結果は積極的な歯周治療は

35週未満の早産または新生児の罹病率を

減少しなかった。

また、積極的な治療を受けた被験者は35週未満の

早産の発症率を増加する可能性が有る。

結論は歯周治療は早産のリスクを

減少しない、ということです。

引用文献

Macones GA, Parry S, Nelson DB, Strauss JF, Ludmir J, Cohen AW, Stamilio DM, Appleby D, Clothier B, Sammel MD, Jeffcoat M.

Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS).

Am J Obstet Gynecol. 2010 Feb;202(2):147.e1-8.