新年、明けましておめでとうございます。
今年もエビデンスを中心に
ブログアップしていきたいと思いますので
宜しくお願い致します。
最初は、MTADという根管洗浄液についての文献です。
これは主に、テトラサイクリン系と
クエン酸と界面活性剤から成ります。
The purpose of this investigation was to compare the antimicrobial effect of MTAD (a mixture of a tetracycline isomer, an acid, and a detergent) with that of NaOCl with and without EDTA. Eighty-five extracted human teeth were contaminated with Enterococcus faecalis for 4 weeks. After biomechanical instrumentation using 1.3% or 5.25% NaOCl as root canal irrigant, the root canal and the external surface of each tooth were exposed to a 5-min application of MTAD, 1.3% NaOCl, 5.25% NaOCl or a 1-min application of EDTA followed by irrigation with 5 ml of 1.3% NaOCl or 5.25% NaOCl. Teeth or dentin shavings were cultured to determine presence or absence of the test bacteria. Fisher’s exact test showed that the combination of 1.3% NaOCl as a root canal irrigant and MTAD as a final rinse was significantly more effective against E. faecalis than the other regimens. The χ2 test showed no difference between the other regimens.
つまり、Group A のMTADで洗浄した時が
Enterococcus faecalis の殺菌効果が最も高かった
ということです。
MTADが最初に報告されたのがこの2003年で
評価はまだこれからだと思いますが
効果が期待できる洗浄液です。
引用文献
Shabahang S, Torabinejad M.
Effect of MTAD on Enterococcus faecalis-contaminated root canals of extracted human teeth.
J Endod. 2003 Sep;29(9):576-9.