今回は毎日の歯磨きの回数と
メタボリックシンドロームの関連についての文献です。
一日の歯磨き回数が1回以下、2回、3回以上の3つに分類し
メタボリックシンドロームの診断指標である中心性肥満
中性脂肪、HDLコレステロール、血圧、空腹時血糖
に加えCRPを評価項目とし
日本人成人925名に調査を行っています。
Inflammation has been strongly related to metabolic syndrome (MetS). Periodontal disease is the most common chronic infection in adults. We investigated a cross-sectional (n = 925) and 3-year longitudinal (n = 685) relationship between the daily frequency of toothbrushing and MetS. In the cross-sectional analysis, the prevalence of MetS was 15.7%. After adjustment for potential confounding factors (including all lifestyle factors), the odds ratios (95% confidence interval [CI]) of having MetS in those who brushed 2 times/day and ≥ 3 times/day were 0.71 (0.48-1.05) and 0.47 (0.24-0.92), respectively, as compared with ratios in those with a toothbrushing frequency of ≤ 1 time/day. Increasing toothbrushing frequency tended to relate inversely to hypertriglyceridemia and high-sensitivity C-reactive protein. In the longitudinal analysis, 99 participants were newly diagnosed with MetS. The adjusted odds ratios (95% CI) of the MetS in participants who brushed 2 times/day and ≥ 3 times/day as compared with participants who brushed ≤ 1 time/day were 0.80 (0.49-1.31) and 0.43 (0.19-0.97), respectively. The frequency of toothbrushing was related inversely only to hypertriglyceridemia, consistent with the cross-sectional analysis. This study found that more frequent toothbrushing is related to a lower prevalence and incidence of MetS. These results suggest that more frequent toothbrushing may contribute to the prevention of MetS due to the inflammation/triglyceride pathway.
結果は
歯磨き回数が1日1回以下の場合、メタボリックシンドロームの
発症率と有病率およびTG値、his-CRP値が
歯磨き回数が2回以上の場合と比べて有意に
増加しており
結論は、歯磨き回数の増加はメタボリックシンドロームの予防に
寄与している可能性があるとのことです。
歯ブラシによる直接的な効果以外にも
歯ブラシをきっかけに生活習慣の見直し等
健康意識の改善による間接的な効果も
影響していそうです。
引用文献
Kobayashi Y1, Niu K, Guan L, Momma H, Guo H, Cui Y, Nagatomi R.
Oral health behavior and metabolic syndrome and its components in adults.
J Dent Res. 2012 May;91(5):479-84.